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Cluster Computing for Improved Processing

Has anyone ever tried employing high performance cluster computing in order to improve processing time of imagery? If so was it simple to set up and reliable? Thanks

I have just spent the month of May trying nearly every Amazon and Microsoft cloud server combination, with a Pix4D trial license (running on Windows Server requires the Enterprise version, not Desktop), and I found no scenario that could match my desktop.  I processed about 40 billion pixels so it was no small job…bigger jobs may require more RAM to be efficient.

CPU: Intel® Core™ i7-5960X CPU @ 3.00GHz
GPU: NVIDIA GeForce GTX 1060 6GB (Driver:

I can go deeper into the iterations if you want to discuss via email, 

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